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学术报告 2018年05月10日(星期四)下午15:00 报告人:Prof. Jörg Kudla
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题 目: Calcium signaling is required for ABA mediated transcriptional adaptation to abiotic stresses
报告人: Prof. Jörg Kudla,Universität Münster, Germany
时 间: 2018年5月10日(星期四) 下午 15:00
地 点: 中国农业大学西校区  生命科学研究中心  一层报告厅

欢迎各位老师和同学踊跃参加!   植物生理学与生物化学国家重点实验室

Abstract:
Calcium and ABA function as central signals in responses to stresses like drought, cold and salinity. Nevertheless, the interrelations between the formation and function of both messengers remained largely enigmatic. Here, I show that the occurrence of calcium signals is pivotal to establish plant stress responses. Accordingly, these calcium signatures are essential and sufficient for inducing ABA accumulation. Calcineurin B-like proteins (CBLs) upon interaction with specific CIPK protein kinases phosphorylate and activate ABA responsive transcription factors. Reconstituting complete calcium and ABA signaling pathways in human cell lines and plant protoplasts, established calcium signaling via specific CBL/CIPK complexes as required and sufficient for ABF2 activation. Together with the phosphorylation analyses of other transcription factors, these results indicate that calcium triggered, CBL/CIPK mediated phosphorylation of transcription factors represents a widespread mechanism to ensure specificity and effectiveness of stress adaptation. I will discuss how this mechanism allows for integration, fine tuning and termination of hormonal and calcium signaling on the level of gene transcription.

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