课题组长

English

李颖章
职称:教授
联系电话:86-10-62732678 (O), 86-1062731304 (L)
E-mail:liyingzhang@cau.edu.cn
研究方向:植物细胞信号转导


 

1982年毕业于北京大学生物系,获理学学士;1982-至今,中国农业大学生物学院工作,并于1992年获硕士学位,2000年获博士学位。1996-1997年,南斯拉夫诺维萨德大学做访问学者。主持国家自然科学基金项目多项。近年来在Plant, Cell and Environment、J Plant Physiol、BMB reports等刊物发表SCI论文多篇。主编、副主编、参编教材多部。

 

主要研究方向

研究方向:
1、植物防卫反应信号转导的调控机制
植物防卫反应中信号途径的启动决定植物抗性反应的差异。近年来,我们实验室主要研究拟南芥抗棉花黄萎病菌毒素防卫反应信号转导的作用机制。我们重点研究NO和H2O2信号参与调控防卫基因表达的作用机制及微管骨架动态在植物防卫反应中功能。已有研究证明,NO和H2O2作为上游信号,调控微管骨架的动态变化。微管骨架在拟南芥抗Vd-toxins防卫反应中起重要作用,微管骨架动态作为信号的转导体,调控下游防卫基因的表达。同时,我们也研究组蛋白H2B单泛素化修饰参与Vd-toxins胁迫应答的作用机制,包括组蛋白H2B单泛素化调控植物抗Vd-toxins防卫反应的作用机制,以及组蛋白H2B单泛素化参与Vd-toxins胁迫应答及调控细胞微管骨架动态的信号途径。

2、大丽轮枝菌致病机理
大丽轮枝菌是引起棉花黄萎病的主要病菌。我们利用农杆菌介导的T-DNA插入(ATMT)法,筛选和寻找大丽轮枝菌致病基因,并纯化有效的激发子分子,研究激发子与植物互作的分子机制。

发表论文/论著    (*通讯作者)

Lin-Lin Yao, Bao-Lei Pei, Qun Zhou, Ying-Zhang Li* (2012) NO serves as a signaling intermediate downstream of H2O2 to modulate dynamic microtubule cytoskeleton during responses to VD-toxins in Arabidopsis. Plant Signaling & Behavior 7(2):1-4
Lin-Lin Yao, Qun Zhou, Bao-Lei Pei, Ying-Zhang Li* (2011) Hydrogen peroxide modulates the dynamic microtubule cytoskeleton during the defense responses to Verticillium dahliae toxins in Arabidopsis. Plant, Cell & Environment, 34:1586-1598 Cover article.
Lin-Lin Yao and Ying-Zhang Li* (2009) NO and H2O2 are involved in the regulation of cortical microtubule depolymerization during the responses to Verticillium dahliae toxins in Arabidopsis. 9th International Plant Molecular Biology Congress. p451. Oct 25-30,St, Louis, USA
Fu-Mei Shi, Lin-Lin Yao, Bao-Lei Pei, Qun Zhou and Ying-Zhang Li* (2009) Cortical microtubule as a sensor and target of nitric oxide signal during the defense responses to Verticillium dahliae toxins in Arabidopsis. Plant, Cell and Environment 32:428-438
Fu-Mei Shi and Ying-Zhang Li* (2008) Verticillium dahliae toxins-induced nitric oxide production in Arabidopsis is major dependent on nitrate reductase. BMB reports 41(1): 79-85
Yan-Yan Hou, Fu-Mei Shi and Ying-Zhang Li* (2008) Verticillium dahliae toxins induced changes of a putative histone H2B and a pumilio /Puf RNA-binding protein gene expression in Arabidopsis thaliana. J Plant Pathol 90 (1):117-120
Zhi-Qi Jia, Fu-Mei Shi, Hai-Yong Yuan, Yan-Yan Hou and Ying-Zhang Li* (2007) Comparison of methods of purification and identification of Verticillium dahliae toxins. J Life Sciences 1:67-72
Jia Zhi-Qi, Yuan Hai-Yong & Li Ying-Zhang* (2007) NO and H2O2 induced by Verticillium dahliae toxins and its influence on the expression of GST gene in cotton suspension cells. Chi Sci Bull 52:1347-1354
Du Juan, Xie Hong-Li, Zhang Deqiang, He Xin-Qiang, Wang Min-Jie, Li Ying-Zhang, Cui Ke-Ming and Lu Meng-Zhu. (2006) Regeneration of secondary vascular system in poplar (Populus tomentosa Carr.) as a novel system to investigate gene expression by a proteomic approach.  Proteomics 6:881-895
Hai-Yong Yuan, Lin-Lin Yao, Zhi-Qi Jia, Yun Li and Ying-Zhang Li* (2006) Verticillium dahliae toxin induced alterations of cytoskeletons and nucleoli in Arabidopsis suspension cells. Protoplasma 229:75-82 Cover article.
Xiao-Hua Zheng, Ying-Zhang Li* (2004) Ultrastructural changes and location of -1,3-glucanase in resistant and susceptible cotton callus cells in response to treatment with toxin of Verticillium dahliae and salicylic acid.  J Plant Physiol 161:1367-1377
Li Ying-Zhang*, Zheng Xiao-Hua, Tang Hai-Lin (2003) Increase of -1,3-glucanase and chitinase activities in cotton callus cells treated by salicylic acid and toxin of Verticillium dahliae Kleb. Acta Bot Sin 45:802-808