课题组长

English

蒋才富

职称:教授

联系电话:86-10-62732331

E-mail:cfjiang@cau.edu.cn

1997年9月–2001年7月:华中师范大学,本科

2001年9月–2004年7月:华中师范大学,硕士

2004年9月–2008年10月:中国科学院遗传与发育生物学研究所,博士

 

2008年11月–2013年11月:牛津大学, 博士后

2013年11月-至今:中国农业大学,教授

主要研究方向

研究方向:植物/作物的逆境胁迫应答机制


1
AtrbohF-ROS介导高盐胁迫应答的分子机制研究

高盐胁迫可诱导植物体内活性氧(ROS)的累积(Munns and Tester, (2008) Annu. Rev. Plant Biol. 59, 651)。我们之前的研究表明AtrbohF(编码一个关键的ROS合成酶)是介导拟南芥高盐胁迫应答的重要基因,AtrbohF功能缺失突变体在高盐环境下ROS积累缺陷、体内积累高浓度的Na、对高盐胁迫十分敏感(Jiang et al., (2012) EMBO J. 31, 4359;Jiang et al., (2013) Plant Cell.)。在此基础上,本实验室将通过抑制突变体筛选等方法深入研究AtrbohF-ROS介导高盐胁迫应答的分子机制。


2玉米逆境胁迫应答相关基因的鉴定及功能研究

玉米是全世界产量最大的作物,它也是重要的遗传学研究材料。玉米B73基因组测序在2009年就已完成(Schnable et al., (2009) Science 326, 1112),在下一代测序技术的推动下,数百个自交系材料的重测序也相继完成(如Lai et al., (2010) Nature Genetics 42, 1027; Jiao et al., (2012) Nature Genetics 44, 812)。在接下来的玉米功能组学的研究中,一个重要研究任务就是分离鉴定与重要农艺性状相关的数量性状基因(quantitative trait loci,QTL)。本实验室将通过GWAS、QTL分析结合传统图位克隆技术来鉴定、研究与玉米抗逆相关的基因。

发表论文/论著    (*通讯作者)

Jiang C#,*, Mithani A#, Belfield EJ, Mott R, Hurst LD, Harberd NP*. (2014) Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations. Genome Res. doi: 10.1101/gr.177659.114. (# equal contribution).

Leach LJ, Belfield EJ, Jiang C, Brown C, Mithani A, Harberd NP*. (2014) Patterns of homoeologous gene expression shown by RNA sequencing in hexaploid bread wheat. BMC Genomics 15: 276.

Belfield EJ, Brown C, Gan X, Jiang C, Baban D, Mithani A, Mott R, Ragoussis J, Harberd NP*. (2014) Microarray-based ultra-high resolution discovery of genomic deletion mutations. BMC Genomics 15: 224.

Jiang C, Belfield EJ, Cao Y, Smith JA, Harberd NP*. (2013) An Arabidopsis soil-salinity-tolerance mutation confers ethylene-mediated enhancement of sodium/potassium homeostasis. Plant Cell 25: 3535-52.

Mithani A, Belfield EJ, Brown C, Jiang C, Leach LJ, Harberd NP*. (2013) HANDS: a tool for genome-wide discovery of subgenome-specific base-identity in polyploids. BMC Genomics 14: 653.

Jiang C, Belfield EJ, Mithani A, Visscher A, Ragoussis J, Mott R, Smith JA, Harberd NP*. (2012) ROS-mediated vascular homeostatic control of root-to-shoot soil Na delivery in Arabidopsis. EMBO J. 31: 4359-70.

Belfield EJ, Gan X, Mithani A, Brown C, Jiang C, Franklin K, Alvey E, Wibowo A, Jung M, Bailey K, Kalwani S, Ragoussis J, Mott R, Harberd NP*. (2012) Genome-wide analysis of mutations in mutant lineages selected following fast-neutron irradiation mutagenesis of Arabidopsis thaliana. Genome Res. 22: 1306-15.

Jiang C, Mithani A, Gan X, Belfield EJ, Klingler JP, Zhu JK, Ragoussis J, Mott R, Harberd NP*. (2011) Regenerant Arabidopsis lineages display a distinct genome-wide spectrum of mutations conferring variant phenotypes. Curr Biol. 21: 1385-90.

Peng ZY, Zhou X, Li L, Yu X, Li H, Jiang Z, Cao G, Bai M, Wang X, Jiang C, Lu H, Hou X, Qu L, Wang Z, Zuo J, Fu X, Su Z, Li S, Guo H* (2009) Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis. Nucleic Acids Res. 37: D975-82.

Jiang C, Gao X, Liao L, Harberd NP, Fu X*. (2007) Phosphate starvation root architecture and anthocyanin accumulation responses are modulated by the gibberellin-DELLA signaling pathway in Arabidopsis. Plant Physiol. 145: 1460-70.

Jiang C, Fu X*. (2007) GA action: turning on de-DELLA repressing signaling. Curr Opin Plant Biol. 10: 461-5.

Achard P, Liao L, Jiang C, Desnos T, Bartlett J, Fu X*, Harberd NP*. (2007) DELLAs contribute to plant photomorphogenesis. Plant Physiol. 143: 1163-72.