植物生理学与生物化学国家重点实验室

English

周文焜

职称：教授

联系电话：86-10-62732678(O); 86-10-62731304(L)

E-mail: zhouwenkun@cau.edu.cn

研究方向：植物适应胁迫信号的干细胞调控机理

学习经历

2002.09 - 2006.06 浙江大学学士

2006.09 - 2013.01 中国科学院遗传与发育生物学研究所博士

工作经历

2013.01 - 2014.03 中国科学院遗传与发育生物学研究所研究助理

2014.04 - 2019.12 荷兰瓦赫宁根大学博士后

2020.04 - 今中国农业大学教授

主要研究方向

植物固着生长的特点决定了其必须通过对生长发育的改变以适应不断变化的环境条件。因此，植物显示出惊人的生长发育可塑性。在长期的进化过程中，植物形成了复杂精细的调控机制以平衡用于生长发育和胁迫反应的资源分配。植物生长发育最初的细胞来源是位于茎端和根端生长点的干细胞。植物能够通过超强的可塑性生长能力适应不断变化的环境条件，暗示植物能够通过干细胞感受逆境信号进而调整生长发育进程。

我们将主要以模式植物和作物玉米根系作为研究对象，通过细胞生物学，遗传学，生物化学，生理学和分子生物学等技术手段来研究植物根干细胞响应生物/非生物胁迫的调控机理。通过研究干细胞感受逆境信号进而调整生长发育进程的分子机理以打破植物抗逆反应和生长发育的负相关，为作物高产高抗遗传改良提供理论指导和技术借鉴。

发表论文/论著（*通讯作者）

发表论文 (^*corresponding author, ^#co-first author)

1. Zhou W^*, and Zhang X. (2021). Molecular mechanism of Verticillium dahliae induced leaf senescence. Mol. Plant doi: https://doi.org/10.1016/j.molp.2021.08.020

2. Zhou W^*. (2021). CIK receptor kinases in root meristem. Mol. Plant 14: 873.

3. Zhai H^#, Zhang X^#, You Y, Lin L, Zhou W^*, and Li C^*. (2020) SEUSS Integrates Transcriptional and Epigenetic Control of Root Stem Cell Organizer Specification. EMBO J. DOI:10.15252/embj.2020105047

4. Zhou W, Lozano J, Blilou I, Zhang X, Zhai Q, Smant G, Li C and Scheres B. (2019) A jasmonate signaling network activates root stem cells and promotes regeneration. Cell 177: 942-956.

5. Zhang X^*, Zhou W^*#, Chen Q, Fang M, Zheng S, Scheres, B and Li C. (2018) Mediator subunit MED31 is required for radial patterning of Arabidopsis roots Proc. Nat. Acad. Sci. USA 115: E5624-E5633. (^#corresponding author, *co-first author)

6. Zhou W^#, Wei L^#, Xu J, Zhai Q, Jiang H, Chen R, Chen Q, Sun J, Chu J, Zhu L, Liu C-M and Li C. (2010) Arabidopsis tyrosylprotein sulfotransferase acts in the auxin/PLETHORA pathway in regulating postembryonic maintenance of root stem cell niche. Plant Cell 22: 3692-3709.

7. Long Y, Stahl Y, Weidtkamp-Peters S, Postma M, Zhou W, Goedhart J, Sánchez-Pérez M, Gadella T, Simon R, Scheres B and Blilou, I. (2017). In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature 548: 97–102.

8. Li H, Torres-Garcia J, latrasse D, Benhamed M, Schilderink S, Zhou W, Kulikova O, Hirt H and Bisseling T. (2017). Plant-specific histone deacetylases HDT½ regulate GIBBERELLIN 2-OXIDASE 2 expression to control Arabidopsis root meristem cell number. Plant Cell 29:2183-2196.

9. Kang J, Yu H, Tian C, Zhou W, Li C, Jiao Y, Liu D. (2014) Suppression of photosynthetic gene expression in roots is required for sustained root growth under phosphate deficiency. Plant Physiol. 165: 1156-1170.

10. Yu X, Pasternak T, Eiblmeier M, Ditengou F, Kochersperger P, Sun J, Wang H, Rennenberg H, Teale W, Paponov I, Zhou W, Li C, Li X, and Palme K. (2013) Plastid-localized glutathione reductase2-regulated glutathione redox status is essential for Arabidopsis root apical meristem maintenance. Plant Cell 25: 4451-4468.

11. Chen R, Jiang H, Li L, Zhai Q, Qi L, Zhou W, Liu X, Li H, Zheng W, Sun J and Li C. (2012) The Arabidopsis mediator subunit MED25 differentially regulates jasmonate and abscisic acid signaling through interacting with the MYC2 and ABI5 transcription factors. Plant Cell 24: 2898-2916.

12. Chen Q, Sun J, Zhai Q, Zhou W, Qi L, Xu L, Jiang H, Qi J, Li X, Palme K and Li C. (2011) The basic helix-loop-helix transcription factor MYC2 directly represses PLETHORA expression during jasmonate-mediated modulation of the root stem cell niche in Arabidopsis. Plant Cell 23: 3335-3352.

13. Sun J, Chen Q, Qi L, Jiang H, Li S, Xu, Y, Liu F, Zhou W, Pan J, Li X, Palme K and Li C. (2011) Jasmonate modulates endocytosis and plasma membrane accumulation of the Arabidopsis PIN2 protein. New Phytol. 191: 360-375.

14. Sun J,Xu Y, Ye S, Jiang H, Chen Q, Liu F,Zhou W, Chen R, Li X,Tietz O, Wu X, Cohen J,Palme K and Li C. (2009) Arabidopsis ASA1 is important for jasmonate-mediated regulation of auxin biosynthesis and transport during lateral root formation. Plant Cell 21: 1495-1511.

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