课题组长

English
王良省
    
职称:教授
联系电话:86-10-62734388 (O)
E-mail:
wangls@cau.edu.cn
研究方向:植物光合作用与活性氧信号转导
教育背景
2001年-2005年,山东大学,理学学士学位
2005年-2008年,清华大学,理学硕士学位
2008年-2012年,清华大学,理学博士学位
工作经历
2012年-2016年,美国康奈尔大学博伊斯汤普逊研究所, 博士后
2016年-2020年,德国慕尼黑大学,助研、博士后
2020年-至今,中国农业大学,教授
主要研究方向
主要研究方向:植物光合作用与活性氧信号转导

        活性氧(Reactive oxygen species, ROS),尤其是单线态氧(singlet oxygen, 1O2),是植物叶绿体进行光合作用的必然副产物,也是造成叶绿体损伤最主要的原因。低浓度的ROS是维持多种生命活动(细胞分裂/分化、诱导开花等)所必须的。在多种胁迫条件下(高光、干旱、高/低温、生物/非生物损伤等),叶绿体中会产生大量的ROS。过量的活性氧会激活信号转导级联反应、降低光合效率、抑制植物生长、引起细胞乃至整棵植株死亡。活性氧介导的、质体到细胞核的反向信号转导途径不仅参与维持质体的正常发育,而且协助质体整合多种环境信号,从而使质体能够对多种胁迫做出精确响应。
        本实验室主要以模式植物拟南芥和农作物玉米为研究对象,以叶绿体为突破口,研究活性氧信号(特别是单线态氧信号)的产生、感知和信号转导过程,挖掘植物响应活性氧胁迫的关键基因,解析植物应对活性氧胁迫的新途径、新机制。使用的研究手段包括但不局限于遗传筛选、深度测序、电镜分析、代谢组学、蛋白组学、生物化学、细胞生物、分子生物学和植物生理学。
发表论文/论著    (*通讯作者)
发表的论文/论著:

1. Wang L, Leister D, Kleine T* (2020). Chloroplast development and gun signaling are independent of the RdDM pathway. Scientific Reports. 10 (1): 15412
2. Wang L*, Leister D, Guan L, Zheng Y, Schneider K, Lehmann M, Apel K, Kleine T (2020). The Arabidopsis SAFEGUARD1 suppresses singlet oxygen-induced stress responses by protecting grana margins. Proceedings of the National Academy of Sciences of the United States of America. 117 (12): 6918-6927.
3. Wang L*, Kleine T (2020). Singlet oxygen and protochlorophyllide detection in Arabidopsis thaliana. In Reactive Oxygen Species: Methods and Protocols, Methods in Molecular Biology. Springer. pp 63-69
4. Wang L*, Apel K (2019). Dose-dependent effects of 1O2 in chloroplasts are determined by its timing and localization of production. Journal of Experimental Botany. 70:29-40.
5. Lee K, Lehmann M, Paul MV, Wang L, Luckner M, Wanner G, Geigenberger P, Leister D, Kleine T* (2019). Lack of FIBRILLIN6 in Arabidopsis thaliana affects light acclimation and sulfate metabolism. New Phytologist. 16246.
6. Sun L, Wang L, Zheng Z, Liu D* (2018). Identification and characterization of an Arabidopsis phosphate starvation-induced secreted acid phosphatase as a vegetative storage protein. Plant Science. 277: 278-284.
7. Wang L, Liu D* (2018) Functions and regulation of phosphate starvation-induced secreted acid phosphatases in higher plants. Plant Science. 271: 108-116.
8. Leister D, Wang L, Kleine T* (2017). Organellar gene expression and acclimation of plants to environmental stress. Frontiers in Plant Science. 8:387.
9. Wang L*, Liu D (2017). Analyses of root-secreted acid phosphatase activity in Arabidopsis. Bio-protocol. 7:7.
10. Wang D, Liu H, Zhai G, Wang L, Shao J, Tao Y* (2016). OspTAC2 encodes a pentatricopeptide repeat protein and regulates rice chloroplast development. Journal of Genetics and Genomics. 43: 601-608.
11. Wang L#, Kim C#, Xu X, Piskurewicz U, Dogra D, Singh S, Mahler H, Apel K* (2016). Singlet oxygen- and EXECUTER1-mediated signaling is initiated in grana margins and depends on the protease FtsH2. Proceedings of the National Academy of Sciences of the United States of America. 113: E3792-E3800.
12. Wang L, Apel K* (2016) Chapter 39 Singlet Oxygen in Higher Plants. In Singlet Oxygen: Applications in Biosciences and Nanosciences, Vol 2. The Royal Society of Chemistry, pp 265-278.
13. Chen S, Kim C, Lee J, Lee H, Fei Z, Wang L, Apel K* (2015). Blocking the QB-binding site of photosystem II by tenuazonic acid, a non–host-specific toxin of Alternaria alternata, activates singlet oxygen-mediated and EXECUTER-dependent signaling in Arabidopsis. Plant, Cell & Environment. 38:1069–1080.
14. Wang L, Lu S, Zhang Y, Liu D* (2014). Comparative genetic analysis of Arabidopsis purple acid phosphatases AtPAP10, AtPAP12, and AtPAP26 provides new insights into their roles in plant adaptation to phosphate deprivation. Journal of Integrative Plant Biology. 56: 299-314.
15. Wang L, Dong J, Gao Z, Liu D* (2012). The Arabidopsis gene HYPERSENSITIVE TO PHOSPHATE STARVATION 3 encodes ETHYLENE OVERPRODUCTION 1. Plant & cell physiology. 53(6): 1093–1105.
16. Wang L, Liu D* (2012). Arabidopsis purple acid phosphatase 10 is a component of plant adaptive mechanism to phosphate limitation. Plant signaling & behavior. 7:3 1-5.
17. Wang L#, Li Z#, Qian W, Guo W, Gao X, Huang L, Wang H, Zhu H, Wu JW, Wang D, Liu D* (2011). The Arabidopsis purple acid phosphatase AtPAP10 is predominantly associated with the root surface and plays an important role in plant tolerance to phosphate limitation. Plant Physiology. 157: 1283-1299.