Fu, Ying
Ph.D., Professor
Tel:86-10-62734395 (O);86-10-62731323 (L)
Areas of Expertise:Plant Cell Growth and Cytoskeleton
2007 – Present   Professor, China Agricultural University, PRC
2004 – 2007     Assistant Project Scientist, University of California, Riverside, USA
1999 – 2004     Postdoc, University of California, Riverside, USA
1993 – 1999     Ph.D. Candidate, Wuhan University, PRC
1989 – 1993     Undergraduate Student, Central China Normal University
Research of Special Interest

Plant cell morphogenesis is critical for different types of cells to fulfill their specialized functions. No mobile plant cells achieve their final morphology through polarized cell growth. The cytoskeleton is a complex network of protein filaments that exists throughout the cytoplasm of eucaryotic cells and plays critical roles in the regulation of many important cellular processes including cell growth and cell shape formation. We investigate how the cytoskeleton is capable of responding to various developmental signals and environmental cues, and modulates plant cell growth. Our recent focus is to reveal specific signals and their signaling pathways leading to the reorganization and dynamics of microtubules and microfilaments for the control of plant cell growth.

Auxin-activated ROP6-RIC1 signaling pathway promotes the ordering of cortical microtubules through regulating the microtubule severing activity of KTN1, the p60 subunit of the microtubule severing protein katanin. (Current Biology. 2013, 23: 290-297)

Publications      *Correspondence Author
Zhu L, Zhang Y, Kang E, Xu Q, Wang M, Rui Y, Liu, B, Yuan M, Fu Y*. 2013. Map18 regulates the direction of pollen tube growth in Arabidopsis by modulating F-actin. The Plant Cell. (online)
Lin D, Cao L, Zhou Z, Zhu L, Ehrhardt D, Yang Z, Fu Y*. 2013. Rho GTPase signaling activates microtubule severing to promote microtubules ordering in Arabidopsis. Current Biology. 23: 290-297
Zhu L, Fu Y*. 2012. Analysis of in vivo ROP GTPase activity at the subcellular level by fluorescence resonance energy transfer microscopy. Plant Signalling Networks, Methods and Protocols. Edited by Wang ZY. and Yang Z. Humana Press. pp 145-152
Lin D, Nagawa S, Chen J, Cao L, Chen X, Li H, Dhonukshe P, Yamamuro C, Friml J, Scheres B, Fu Y, Yang Z. 2012. A ROP GTPase-dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots. Current Biology. 22: 1319-1325
Nagawa S, Xu T, Lin D, Dhonukshe P, Zhang X, Friml J, Scheres B, Fu Y, Yang Z. 2012. ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis. PLoS Biology. 10(4): e1001299. doi:10.1371/journal.pbio.1001299
Fu Y, Yang Z. 2011. Signaling to the cytoskeleton in diffuse cell growth. The Plant Cytoseleton. Edited by Liu B. Springer Science+Business Media, LLC. Vol 2, pp 229-243
Xu T, Wen M, Nagawa S, Fu Y, Chen JG, Wu MJ, Perrot-Rechenmann C, Friml J, Jones AM, Yang Z. 2010. Cell surface- and Rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis. Cell. 143: 99-110
Fu Y*. 2010. ROP GTPases and the Cytoskeleton. Integrated G Proteins Signaling in Plants. Edited by Yalovsky S. et al. Springer-Verlag Berlin Heidelberg. pp 91-104
Fu Y*. 2010. The actin cytoskeleton and signaling network during pollen tube tip growth. Journal of Integrative Plant Biology. 52: 131-137
Fu Y*, Xu T, Zhu L, Wen M, Yang Z*. 2009. A ROP GTPase signaling pathway controls cortical microtubule ordering and cell expansion in Arabidopsis. Current Biology.19: 1827-1832
Zhou L, Fu Y* and Yang, Z*. 2009. A genome-wide functional characterization of Arabidopsis regulatory calcium sensors in pollen tubes. Journal of Integrative Plant Biology. 51: 751-61
Jeon BW, Hwang JU, Hwang Y, Song WY, Fu Y, Gu Y, Bao F, Cho D, Kwak JM, Yang Z, Lee Y. 2008. The Arabidopsis small G protein ROP2 is activated by light in guard cells and inhibits light-induced stomatal opening. Plant Cell. 20: 75-87
Fu Y, Yang Z, Kawasaki T, Shimamoto K. 2008. ROP/Rac GTPases. Chapter 3 in Intracellular Signalling in Plants. Edited by Yang Z. Blackwell Publishing, Oxford, UK. pp 64-99
Yang Z, Fu Y. 2007. ROP/RAC GTPase signaling. Current Opinion in Plant Biology. 10: 490-494
Fu Y, Gu Y, Zheng Z, Wasteneys G, and Yang Z. 2005. Arabidopsis Interdigitating Cell growth requires two antagonistic pathways with opposing action on cell morphogenesis. Cell. 120: 687-700
Gu Y, Fu Y, Dowd P, Li S , Vernoud V, Gilroy  S, and Yang Z. 2005. A Rho family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. Journal of Cell Biology. 169: 127-138
Fu Y, Li H, Yang Z. 2002.  The Rop2 GTPase controls the formation of cortical fine F-actin and the early phase of directional cell expansion during Arabidopsis organogenesis. The Plant Cell. 14: 777-794
Fu Y, Wu G., Yang Z. 2001.  Rop GTPase-Dependent dynamics of tip-localized F-actin controls tip growth in pollen tubes. Journal of Cell Biology. 152: 1019-1032
Fu, Y. and Yang Z.  2001.  The Rop GTPase: A master switch of cell polarity development in plants.  Trends in Plant Science 6: 545-547
Gu Y, Vernoud V, Fu Y, and Yang Z.  2003. ROP GTPase regulation of pollen tube growth through the dynamics of tip-localized F-actin. Journal of Experimental Botany. 54: 93-101
Jones MA, Shen J, Li H, Fu Y, Yang Z , Grierson CS.  2002.  The Arabidopsis Rop2 GTPase is a Positive Regulator of both Root Hair Initiation and Tip Growth. The Plant Cell.  14: 763-776.
Yuan M1, Fu Y,1 Wang F, Huang B-Q, Zee, S-Y.  and Hepler PK. 2002. Fertilization in Torenia fournieri: actin organization and nuclear behavior in the central cell and primary endosperm. Science in China. 45: 211-224 1Co-first authors
Fu Y, Yuan M, Huang B-Q, Yang H-Y, Zee S-Y, and O’Brien TP. 2000. Changes in actin organization in the living egg apparatus of Torenia  fournieri during fertilization. Sexual Plant Reproduction. 12: 315-322
Huang B-Q, Fu Y, Zee S-Y and Hepler P. 1999. Three-dimensionalorganization and dynamic changes of the actin cytoskeleton in embryo sacs of Zea mays and Torenia fournieri. Protoplasma. 209: 105-119